Diet for gout
(2015) Global epidemiology of gout: prevalence, incidence and risk factors. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Conclusions Higher levels of meat and seafood consumption are associated with an increased risk of gout, whereas a higher level of consumption of dairy products is associated with a decreased risk. (2015) Association of apolipoprotein E (ApoE) polymorphisms with risk of primary hyperuricemia in Uygur men, Xinjiang, China. Lakshmaiah. Kaneko. Gout itself is an interesting example because it is a disease that has gone out of fashion in the last century and yet the latest reports suggest it is not only as prevalent as ever, but becoming more so. Sathisha, Shubha Gopal, Kanchugarakoppal S. Of these 76 men, 26 (34 percent) did not have relevant and complete records. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. (2016) Hyperuricemia, the kidneys, and the spectrum of associated diseases: a narrative review. Grainge, Weiya Zhang, Michael Doherty. (2016) Update on Importance of Diet in Gout. The influence of high protein diets on the endogenous uric acid elimination. Kovesdy, Kamyar Kalantar-Zadeh. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Overall, however, our findings provide prospective evidence that meat consumption and seafood consumption are associated with an increased risk of gout, whereas consumption of dairy products, especially low-fat dairy products, is associated with a substantially reduced risk of gout. Until the late 17th century, when the spread of gout reached almost epidemic proportions in Britain, the disease afflicted almost exclusively the nobility, the rich and the educated, and so those who could afford to indulge an excessive appetite for food and alcohol. CrossRef 59 Gim Gee Teng, An Pan, Jian-Min Yuan, Woon-Puay Koh. Jing, J. Reproducibility and validity of an expanded self-administered semiquantitative food frequency questionnaire among male health professionals. CrossRef 6 Ping Zhao, Ke-li Chen, Guo-li Zhang, Guang-rui Deng, Juan Li. Fish and omega-3 fatty acid intake and risk of coronary heart disease in women. Cricelli, F. Statistical Analysis We computed the person-time of follow-up for each man as the interval between the date on which the 1986 questionnaire was returned and the date of a diagnosis of gout, death from any cause, or the end of the study period, whichever came first. I wanted to show the writing process at its mid-point. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. G. Jalal. Effect of oral purines on serum and urinary uric acid of normal, hyperuricemic and gouty humans. (2015) Gout and Hyperuricemia: an Historical Perspective. The association between gout and nephrolithiasis: the National Health and Nutrition Examination Survey III, 1988-1994. To examine these issues, we prospectively evaluated the relationship between the reported intake of purine-rich foods, dairy foods, and protein and the incidence of gout in a cohort of 47,150 men who had no history of gout at base line. We prospectively investigated the association of these dietary factors with new cases of gout. Other variables considered in multivariate models included age (as a continuous variable), alcohol use (in seven categories), body-mass index (the weight in kilograms divided by the square of the height in meters, in six categories), the use or nonuse of diuretics, history of hypertension (yes or no), history of chronic renal failure (yes or no), and fluid intake (in quintiles). Richette. Adobe Flash Player is required to view this feature. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Beyl, Laura Hughes, Sarah Morgan. Adobe Flash Player is required to view this feature. Allison, Jasvinder A. CrossRef 13 Kyoung-Bok Min, Jin-Young Min. Desideri, J. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. In order to represent the long-term dietary patterns of individual men, our primary analysis used cumulative average dietary intakes based on the information from the 1986, 1990, and 1994 dietary questionnaires. Yamada, C. A higher total intake of animal or vegetable protein was not associated with an increased risk of gout. Influence of various purines on uric acid metabolism. Adobe Flash Player is required to view this feature. Mandell. (2015) The management of hyperuricemia with urate deposition. Cui, S. 5 In addition, the bioavailability of various purines contained in different foods varies substantially. Adobe Flash Player is required to view this feature. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Stamp, Leslie G. The rate of follow-up for this cohort exceeded 90 percent during the study period. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 36:8, 906-922. Adobe Flash Player is required to view this feature. Bone and Rheumatic Disorders in Diabetes. Adobe Flash Player is required to view this feature. CrossRef 30 Shasha Yu, Hongmei Yang, Xiaofan Guo, Xingang Zhang, Ying Zhou, Qiaoyun Ou, Liqiang Zheng, Yingxian Sun. Lanaspa, Takahiko Nakagawa, Richard J. Topless, Richard Day, Diluk Kannangara, Kenneth Williams, Malcolm Smith, Matthijs Janssen, Tim L. I. Furthermore, when we evaluated the effect of various definitions of gout, our findings appeared to be robust, and the magnitude of the associations tended to increase with increasing specificity of the case definition. CrossRef 47 Hong Du, Chang-yan Dong, Qiao-yan Lin. Kielstein, U. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. CrossRef 55 Joseph F Merola, Shaowei Wu, Jiali Han, Hyon K Choi, Abrar A Qureshi. Choi. Johnson. Kano, N. (2015) Sleep Apnea and the Risk of Incident Gout: A Population-Based, Body Mass Index-Matched Cohort Study. (2015) Gout and its comorbidities in the total population of Stockholm. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Eighty-eight percent of the men with gout reported podagra, 35 percent midfoot involvement, 72 percent hyperuricemia, and 11 percent a tophus. (2016) Gout in Older Adults: The Atherosclerosis Risk in Communities Study. Schultheiss, T. Renal urate excretion in gout studied by feeding ribonucleic acid. Dietary fat intake and the risk of coronary heart disease in women. To confirm the validity of the criteria for gout used in the survey in our cohort, two board-certified rheumatologists reviewed the medical records of a sample of 76 of the men who had reported having gout and had consented to the release of their medical records. (2016) Gouty Arthritis: A Review of Acute Management and Prevention. The reference group for the comparisons in Panels D, E, and F was the men in the lowest quintile for intake of the given food group who did not drink alcohol. But once gout became easily treatable, in the early 1960s, with the discovery of the drug allopuranol, clinical investigators and researchers began to lose interest. Studies in uric acid metabolism. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Fukuuchi, K. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Peloquin, Maureen Dubreuil, Edward Roddy, Na Lu, Tuhina Neogi, Hyon K. (2015) Relationship between hyperuricemia and dietary risk factors in Chinese adults: a cross-sectional study. e2. CrossRef 32 Ramin Alemzadeh, Jessica Kichler. First, little is known about the precise identity and quantity of individual purines in most foods, especially when they are cooked or processed. Adobe Flash Player is required to view this feature. Drs. Quinn, Jonathan Hewitt, Yuhua Fan, Jesse Dawson. CrossRef 37 Mehmet Kanbay, Thomas Jensen, Yalcin Solak, Myphuong Le, Carlos Roncal-Jimenez, Chris Rivard, Miguel A. T. In our study, fulfillment of 6 of the 11 American College of Rheumatology survey criteria for gout 13 showed a high degree of concordance with reviews of the medical records, and the incidence of gout fulfilling these criteria in our cohort agreed closely with the estimated incidence among male physicians in the Johns Hopkins Precursor Study 1 (1. Diet was assessed every four years by means of a food-frequency questionnaire. To assess the trends, we used the median values of intake in each category, so as to minimize the influence of outliers. The chapter addresses important misconceptions about diet, fructose, blood pressure, and diabetes through the lens of gout. (2016) Effects of the Dietary Approaches to Stop Hypertension (DASH) Diet and Sodium Intake on Serum Uric Acid. Gout and the condition known technically as hyperuricemia, or elevated levels of uric acid, are the most recent examples of this kind of institutional neglect of the potential health effects of fructose, and how pervasive it can be. As in other epidemiologic studies of gout, 1,23,32-34 our primary case definition of gout did not require the observation of urate crystals in joint fluid. Adobe Flash Player is required to view this feature. CrossRef 46 Yu-Ping Sun, Bei Zhang, Lei Miao, Xian-Min Wang, Jia-Hui Yu, Li Luo, Lu Ying, Gao Xin, Gulinizha Haliakpaer, He Xia, Hua Yao. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Ronald MacKenzie. CrossRef 40 Richard J. Gladden, Mustafa Ahmed, Ali Ahmed, Gerasimos Filippatos. (2017) Pharmacological Basis for Use of. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Appel, Edgar R. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. I have bolded several sections for those who would like a 2-3-minute skim of content highlights before digesting the entire piece, which is 7 pages long. (2016) Identification of Adenine and Benzimidazole Nucleosides as Potent Human Concentrative Nucleoside Transporter 2 Inhibitors: Potential Treatment for Hyperuricemia and Gout. 10,12 Potentially biased recall of diet was avoided, because the intake data were collected before gout was diagnosed. Gout and coronary heart disease: the Framingham Study. Milk- and soy-protein ingestion: acute effect on serum uric acid concentration. Singh. Taylor, Tuhina Neogi. Only 11 percent had undergone arthrocentesis, and of these, 65 percent reported having urate crystals in their joint fluid. CrossRef 21 Z. (2015) No development of hypertension in the hyperuricemic liver-Glut9 knockout mouse. Adobe Flash Player is required to view this feature. Adobe Flash Player is required to view this feature. Assessment of Diet To assess dietary intake, we used a semiquantitative food-frequency questionnaire that inquired about the average consumption of more than 130 foods and beverages during the previous year. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Journal of the Science of Food and Agriculture 97:2, 520-525. Adobe Flash Player is required to view this feature. Sayre, Hyon K. (2016) Correlation of blood uric acid with urinary albumin creatinine ratio in hypertension and diabetic nephropathy. Adobe Flash Player is required to view this feature. CrossRef 53 Takahiro Ueda, Shinichi Honda, Hideyuki Morikawa, Shiro Kitamura, Yoshitaka Iwama, Kaku Nakagawa. Yamaoka, K. We assessed possible effect modification by food groups and by alcohol use (or nonuse) or the body-mass index ( Results During the 12-year follow-up, we documented 730 confirmed new cases of gout that met the criteria of the American College of Rheumatology. In multivariate models of nutrient density, 16 we simultaneously included energy intake, the percentages of energy derived from fat and specific types of protein, and other potentially confounding variables. CrossRef 3 Christina Park, Yoshitsugu Obi, Elani Streja, Connie M. McAdams-DeMarco. Adobe Flash Player is required to view this feature. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Among the remaining 50 men, the rate of concordance between the diagnosis of gout according to the criteria of the American College of Rheumatology and the diagnosis of gout according to our review of the medical records was 94 percent (47 of 50). Adobe Flash Player is required to view this feature. Citing Articles 1 Hossam El-Zawawy, Brian F. Our study overcame these hurdles by examining common foods or food groups and new cases of gout, and it provides clinically relevant information: each additional daily serving of meat was associated with a 21 percent increase in the risk of gout, and each additional weekly serving of seafood was associated with a 7 percent increase in risk. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Adobe Flash Player is required to view this feature. 5 and 1. The reference group for the comparisons in Panels A, B, and C was the men in the lowest quintile for intake of the given food group who had a body-mass index (BMI) of less than 25. Adobe Flash Player is required to view this feature. Adobe Flash Player is required to view this feature. The actual evidence, however, has always been less-than-compelling: Just as low cholesterol diets have only a trivial effect on serum cholesterol levels, for instance, and low-salt diets have a clinically insignificant effect on blood pressure, low-purine diets have a negligible effect on uric acid levels. Adobe Flash Player is required to view this feature. Levels of purines in foods and their metabolic effects in rats. Nutrition and Rheumatic Diseases. Adobe Flash Player is required to view this feature. Adobe Flash Player is required to view this feature. CrossRef 42 Humaira Rasheed, Cushla McKinney, Lisa K. A controlled study of diet in patients with gout. When we used other definitions of gout, the magnitude of the associations with particular food groups tended to increase as the specificity of the case definition increased, but null associations remained null. (2016) Serum urate gene associations with incident gout, measured in the Framingham Heart Study, are modified by renal disease and not by body mass index. 17 Clifford AJ, Riumallo JA, Young VR, Scrimshaw NS. Lindegaard, Jesper Hallas. CrossRef 7 Andrew Grey, Nicola Dalbeth. These results suggest that there may be a substantial difference between these subgroups in purine-to-uric-acid metabolism, uric acid excretion specifically related to seafood intake, or both. Preliminary criteria for the classification of the acute arthritis of primary gout. A case-control study of alcohol consumption and drinking behaviour in patients with acute gout. Media in This Article Figure 1 Multivariate Relative Risk of a New Case of Gout According to Quintile of Intake of Various Food Groups and Body-Mass Index (Panels A, B, and C) or Alcohol Use or Nonuse (Panels D, E, and F). If you are using an operating system that does not support Flash, we are working to bring you alternative formats. CrossRef 23 Gang Chen, Ping Jia.
This made gout the original example of a disease linked to diet and over-consumption, and so, in effect, the original disease of civilization. (2015) Allopurinol adherence among patients with gout: an Italian general practice database study. New York: Oxford University Press, 1998. The relative risks were adjusted for age, total energy intake, body-mass index, use or nonuse of diuretics, presence or absence of a history of hypertension, presence or absence of a history of renal failure, and intake of alcohol, fluid, total meats, seafood, purine-rich vegetables, and dairy foods. Discussion In this large prospective cohort study involving men, we found an increased risk of gout with higher meat consumption or seafood consumption but not with higher consumption of animal or vegetable protein or purine-rich vegetables. (2016) Evaluation of purine utilization by. (2016) Uric acid in metabolic syndrome: From an innocent bystander to a central player. Adobe Flash Player is required to view this feature. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Adobe Flash Player is required to view this feature. Prabhavathi, Madhavi Reddy, V. Carlsson, Gunnar Ljunggren. CrossRef 12 N. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. (2016) Assay systems for screening food and natural substances that have anti-hyperuricemic activity: uric acid production in cultured hepatocytes and purine bodies-induced hyperuricemic model mice. Pontremoli, C. Responses regarding the individual food items were converted to average daily servings. CrossRef 24 Liza Wilson, Joseph J. Recent surveys suggest that nearly 6 percent of all American men in their fifties suffer from gout, and over ten percent in their seventies. 14,15 We used Cox proportional-hazards modeling to estimate the multivariate relative risk of a new case of gout (SAS software, SAS Institute). The average daily intake of each food group was categorized into quintiles. Furthermore, we found a strong inverse association between the consumption of dairy products, especially low-fat dairy products, and the incidence of gout. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. (2016) The consumption of fish cooked by different methods was related to the risk of hyperuricemia in Japanese adults: A 3-year follow-up study. (2015) Risk factors of acute myocardial infarction in middle-aged and adolescent people ( BMC Cardiovascular Disorders 15:1. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Miller. Purine-Rich Foods Increased meat intake was associated with an increased risk of gout. 6 percent) reported a history of gout on the base-line questionnaire. Adobe Flash Player is required to view this feature. Ascertainment of New Cases of Gout On each biennial questionnaire, the men indicated whether they had received a diagnosis of gout from a physician. Consumption of Dairy Products The incidence of gout decreased with increasing intake of dairy products ( Table 3 ). If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Methods Study Population The Health Professionals Follow-up Study is an ongoing longitudinal study involving 51,529 male dentists, optometrists, osteopaths, pharmacists, podiatrists, and veterinarians who were 40 to 75 years of age in 1986. Rangappa. The American Journal of Medicine 129:3, 299-306. CrossRef 31 Kazuya Tatani, Masahiro Hiratochi, Norihiko Kikuchi, Yu Kuramochi, Shinjiro Watanabe, Yuji Yamauchi, Fumiaki Itoh, Masayuki Isaji, Satoshi Shuto. Huang, H. Iwamoto, H. (2016) Uric Acid-Induced Inflammation Is Mediated by the Parathyroid Hormone:25-Hydroxyvitamin D Ratio in Obese Adolescents. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 71:4, 536-542. Similarly, the possibility that the consumption of dairy products has a role in protecting against gout has been raised by metabolic studies. Ren, C. Saseen. CrossRef 22 Shin-ichi Adachi, Fumiaki Yoshizawa, Kazumi Yagasaki. (2016) Urate Handling in the Human Body. Uric acid production of men fed graded amounts of egg protein and yeast nucleic acid. Adobe Flash Player is required to view this feature. Racial differences in the incidence of gout: the role of hypertension. Lindegaard, Jesper Hallas, Suminori Akiba. Confirmation of these findings by future studies might result in more refined and comprehensive dietary recommendations for the prevention of gout, given the emerging role of fish intake in the prevention of coronary heart disease. Yamaoka, T. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. (2017) Anti-hyperuricemic effect of taxifolin in cultured hepatocytes and model mice. (2016) Allopurinol decreases serum uric acid level and intestinal glucose transporter-5 expression in rats with fructose-induced hyperuricemia. Incidence and risk factors for gout in white men. Adobe Flash Player is required to view this feature. The influence of dairy products on plasma uric acid in women. The relative risks were adjusted for age, total energy intake, body-mass index, use or nonuse of diuretics, presence or absence of a history of hypertension, presence or absence of a history of renal failure, and intake of alcohol, fluid, total meats, seafood, purine-rich vegetables, and dairy foods. Adobe Flash Player is required to view this feature. (2015) Chrysanthemum flower oil inhibits diet-induced serum uric acid elevation in adult male subjects. Adobe Flash Player is required to view this feature. Adobe Flash Player is required to view this feature. Dietary protein and risk of ischemic heart disease in women. Momma, Y. Adobe Flash Player is required to view this feature. (2016) Relation of serum uric acid to cardiovascular disease. CrossRef 15 Monica Weiler, Helga Schmetzer, Marion Braeu, Raymund Buhmann. Adobe Flash Player is required to view this feature. 2016. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Buda, R. Miner. These associations were independent of both the other dietary factors we studied and other purported risk factors for gout, such as high body-mass index, older age, hypertension, alcohol use, use of diuretics, and chronic renal failure. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Puig, P. (2016) Effects of coffee consumption on serum uric acid: systematic review and meta-analysis. (2017) Update on Crystal-Induced Arthritides. Adobe Flash Player is required to view this feature. 7 per 1000 person-years, respectively). 10,11 The dietary information was updated in 1990 and 1994. Adobe Flash Player is required to view this feature. Last week, I had a wonderful conversation with Gary Taubes, my favorite science journalist and author of the incredible (and I consider definitive), Good Calories, Bad Calories. Adobe Flash Player is required to view this feature. (2015) Psoriasis, psoriatic arthritis and risk of gout in US men and women. Table 1 Incidence of Gout among Men, According to Five-Year Age Groups. Adobe Flash Player is required to view this feature. (2016) Hyperuricemia is associated with increased hospitalization risk and healthcare costs: Evidence from an administrative database in Italy. AGE 38. Supported in part by grants (DK58573 and CA55075) from the National Institutes of Health and by TAP Pharmaceuticals. 27 We did not find a significant association between gout and the consumption of purine-rich vegetables, either as a group or individually. Adobe Flash Player is required to view this feature. Lawrence Edwards. (2015) Food Sources of Protein and Risk of Incident Gout in the Singapore Chinese Health Study. We used a supplementary questionnaire to ascertain whether participants met the American College of Rheumatology survey criteria for gout. 2nd ed. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Protein intake (animal protein, dairy protein, nondairy animal protein, vegetable protein, and total protein) was also categorized into quintiles according to the percentage of total energy obtained from each type of protein (the nutrient density 16 ). (2017) Serum uric acid, protein intake and mortality in hemodialysis patients. (2016) Increased risk for hyperuricemia in adults sensitized to cow milk allergen. CrossRef 63 J. (2016) Effect of Allopurinol on Cardiovascular Outcomes in Hyperuricemic Patients: A Cohort Study. Adobe Flash Player is required to view this feature. Saragoni, S. In contrast, moderate intake of purine-rich vegetables or protein is not associated with an increased risk of gout. Choi and Curhan report having received a grant from TAP Pharmaceuticals. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Similarly, intake of individual purine-rich vegetable items was not associated with the risk of gout. Serum uric acid correlates in elderly men and women with special reference to body composition and dietary intake (Dutch Nutrition Surveillance System). Nutritional epidemiology. (2016) The rising prevalence and incidence of gout in British Columbia, Canada: Population-based trends from 2000 to 2012. Effect of low level lead exposure on hyperuricemia and gout among middle aged and elderly men: the Normative Aging Study. Nagatomi. Asami. (2016) Prevalence of hyperuricemia and its correlates in rural Northeast Chinese population: from lifestyle risk factors to metabolic comorbidities. Niu, R. Sugiyama, K. Adobe Flash Player is required to view this feature. Actually, our results regarding vegetable-protein intake suggest that protein from vegetable sources may have a protective effect, although its magnitude appeared to be smaller than that provided by dairy protein. Adobe Flash Player is required to view this feature. The participants returned a mailed questionnaire in 1986 concerning diet, medical history, and medications. (2016) Antihyperuricemic effects of thiadiazolopyrimidin-5-one analogues in oxonate treated rats. (2016) Evaluation of cellular purine transport and metabolism in the Caco-2 cell using comprehensive high-performance liquid chromatography method for analysis of purines. Although other nutrients in dairy products may be responsible for the inverse association, there is currently no relevant biologic or metabolic evidence available. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. CrossRef 14 Diana I. Abstract Background Various purine-rich foods and high protein intake have long been thought to be risk factors for gout. Cleland. Kobayashi, N. For the men who did not return the supplementary gout questionnaire, follow-up data were censored at the time of their first report of gout. Our study was substantially larger than previous studies concerning gout, 1,5,23,32-35 and dietary data were prospectively collected and validated. CrossRef 62 Frederic Preitner, Anabela Pimentel, Salima Metref, Corinne Berthonneche, Alexandre Sarre, Catherine Moret, Samuel Rotman, Gabriel Centeno, Dmitri Firsov, Bernard Thorens. Our findings are most directly generalizable to men 40 years of age or older (the population with the highest prevalence of gout 23 ) who have no history of gout. Choi. Methods Over a 12-year period, we prospectively examined the relationship between purported dietary risk factors and new cases of gout among 47,150 men who had no history of gout at base line. We found a strong inverse relation between consumption of dairy products, especially low-fat dairy products, and the incidence of gout. (2016) Gout Classification Criteria: Update and Implications. 2017. Reproducibility and validity of food intake measurements from a semiquantitative food frequency questionnaire. The level of consumption of purine-rich vegetables was not associated with the risk of gout ( Table 3 ). If you are using an operating system that does not support Flash, we are working to bring you alternative formats. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Several strengths and potential limitations of our study deserve comment. Results During the 12 years of the study, we documented 730 confirmed new cases of gout. The reference group for the comparisons in Panels D, E, and F was the men in the lowest quintile for intake of the given food group who did not drink alcohol. Asymptomatic hyperuricemia: risks and consequences in the Normative Aging Study. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Borghi. CrossRef 29 David Hyndman, Sha Liu, Jeffrey N. A history of hypertension was slightly more common among the men in the highest quintile of protein intake than among the men in the other quintiles ( Table 2 ). The reference group for the comparisons in Panels A, B, and C was the men in the lowest quintile for intake of the given food group who had a body-mass index (BMI) of less than 25. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. When we repeated these analyses using energy-adjusted protein values 16 instead of the percentage of total energy accounted for by a given type of protein, the results did not materially change. (2016) Serum uric acid level and association with cognitive impairment and dementia: systematic review and meta-analysis. Of the 49,932 men who provided complete dietary information, 2782 (5. Adobe Flash Player is required to view this feature. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Lapi. T. (2016) Inhibitory effect of extracellular purine nucleotide and nucleoside concentrations on T cell proliferation. (2016) A cross-sectional internet-based patient survey of the management strategies for gout. Moderate intake of purine-rich vegetables or protein is not associated with an increased risk of gout. CrossRef 44 Xue Li, Peige Song, Junping Li, Peiyu Wang, Guowei Li. Effect of ribomononucleotides given orally on uric acid production in man. Increased intake of all individual seafood items was associated with an increased risk of gout (P for trend Table 4 ). These men were excluded from our analysis, leaving 47,150 participants. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Adobe Flash Player is required to view this feature. CrossRef 2 Shin-ichi Adachi, Ken-ichi Nihei, Yoshiyuki Ishihara, Fumiaki Yoshizawa, Kazumi Yagasaki. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Reproducibility and validity of a semiquantitative food frequency questionnaire. Adobe Flash Player is required to view this feature. Adobe Flash Player is required to view this feature. CrossRef 36 Kyu Yong Park, Hyun Jung Kim, Hyeong Sik Ahn, Sun Hee Kim, Eun Ji Park, Shin-Young Yim, Jae-Bum Jun. Although the presence of a tophus or urate crystals in joint fluid would be diagnostic of gout, 13 the sensitivity of these findings is too low, especially in a population-based study, because arthrocentesis is performed infrequently. Kaneko, Y. (2016) Impact of Urate Level on Cardiovascular Risk in Allopurinol Treated Patients.
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